Influence of the Tumor Microenvironment on Cancer Cells Metabolic Reprogramming
As with castles, tumor cells are fortified by surrounding non-malignant cells, such as cancer-associated fibroblasts, bolia outlet gent immune cells, but also nerve fibers and extracellular matrix.In most cancers, this fortification creates a considerable solid pressure which limits oxygen and nutrient delivery to the tumor cells and causes a hypox